Collecting thousands of ultrathin sections
for 3D Correlative Light and Electron Microscopy (CLEM)
with our groundbreaking Magnetic Collection technology
Large CLEM experiments on a single substrate
The video shows 200 consecutive ultrathin sections (50 nm thick)
collected with MagC, immunostained, and imaged with
standard widefield fluorescence Light Microscopy
followed by Scanning Electron Microscopy.
Browse the CLEM wafer yourself:
(powered by neuroglancer and neurodataviz)
Press "?" in the top left corner for navigation help
Collectome
Volumetric CLEM made easy
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Decouple image acquisition from tissue sectioning
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No handling of an intermediate tape
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500 consecutive sections
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50 nm thick
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3-channel Light Microscopy
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10 nm pixel size Electron Microscopy
Your entire 3D experiment on a wafer
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Easy Correlative Light and Electron Microscopy (CLEM)
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Flexible automated workflows in scanning microscopes
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Scanning Electron Microscopes (SEM)
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Fluorescent Light Microscopes (LM, upright or inverted widefield)
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Super-resolution Light Microscopy (STED, PALM, STORM)
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nanoSIMS
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Cathodoluminescence (CL)​
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Easy to share / Easy to ship
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Store your sections for years
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Coordinates of sections automatically determined by us
or with our online SectionFinder app (location and angle)
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Fully automated acquisition of whole wafers
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Define custom imaging workflows
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custom ROIs for all sections
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low resolution overviews
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easily acquire one every n section or any custom range
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Interactive navigation through thousands of sections inside your electron microscope
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Image or re-image any section anytime
th
Beta version released
October 2019
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Get it here and try it out in simulation mode
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The MagC module has seamlessly run for more than 24 hours to acquire mosaics in 433 consecutive Drosophila brain sections yielding a 3D EM dataset of 150 μm x 120 μm x 30 μm
Ideal for Multibeam Electron Microscopy
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Load simultaneously thousands of sections
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High conductivity of the silicon wafer substrate allows high probe currents without charging
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No conductive coating needed
Section collected with MagC and imaged with a Zeiss MultiSEM 91-beam
Scanning Electron Microscope
Whole Drosophila brain on a single wafer
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2500 consecutive sections
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120 nm section thickness
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1 single 100 mm ⌀ wafer
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Easily combine the best of LM and EM
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Multicolor LM
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High-resolution scanning EM